- Crew: 5 (pilot, copilot, weapon systems officer, navigator, electronic warfare officer, and tail gunner until the removal of the tail gun in 1991)
- Length: 159 ft 4 in (48.5 m)
- Wingspan: 185 ft 0 in (56.4 m)
- Height: 40 ft 8 in (12.4 m)
- Wing area: 4,000 sq ft (370 m²)
- Airfoil: NACA 63A219.3 mod root, NACA 65A209.5 tip
- Empty weight: 185,000 lb (83,250 kg)
- Loaded weight: 265,000 lb (120,000 kg)
- Max. takeoff weight: 488,000 lb (220,000 kg)
- Fuel capacity: 47,975 U.S. gal (39,948 imp gal; 181,610 L)
- Zero-lift drag coefficient: 0.0119 (estimated)
- Drag area: 47.60 sq ft (4.42 m²)
- Aspect ratio: 8.56
- Powerplant: 8 × Pratt & Whitney TF33-P-3/103 turbofans, 17,000 lbf (76 kN) each
- Maximum speed: 560 kn (650 mph, 1,047 km/h)
- Cruise speed: 442 kn (525 mph, 844 km/h)
- Combat radius: 4,480 mi (3,890 nmi, 7,210 km)
- Ferry range: 10,145 mi (8,764 nmi, 16,232 km)
- Service ceiling: 50,000 ft (15,000 m)
- Rate of climb: 6,270 ft/min (31.85 m/s)
- Wing loading: 120 lb/ft² (586 kg/m²)
- Thrust/weight: 0.31
- Lift-to-drag ratio: 21.5 (estimated)
- Guns: 1× 20 mm (0.787 in) M61 Vulcan cannon originally mounted in a remote controlled tail turret on the H-model, removed from all current operational aircraft in 1991
- Bombs: Approximately 70,000 lb (31,500 kg) mixed ordnance; bombs, mines, missiles, in various configurations.
